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Description

Gastroenterology (2014) 146(7):173951.e14

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5-Amino-1MQ (5-amino-1-methylquinolinium) is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme involved in cellular energy metabolism

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In contrast, QA promotes glutamate release in rodent synaptosomes, inhibits astrocytic glutamate uptake, and reduces glutamine synthase activity [83,84,85]

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